The Role of Catastrophizing in Enhancing Pain Interference and Depressive Symptoms in Endometriosis: A Longitudinal Examination

This longitudinal study investigates for the first time the impact of pain catastrophizing on pain interference and depressive symptoms over time in cisgender women with endometriosis. Findings indicated both a direct influence of pain catastrophizing on depressive symptomatology and an indirect effect via increased pain interference, in line with the Fear-Avoidance Model. These findings underscore the importance of targeting pain catastrophizing tendencies in interventions aimed at improving the well-being of patients affected by endometriosis.