Digital biomarker for assessing executive function in a remote iPACES clinical trial for mild cognitive impairment: The comparability of the electronic Stroop vs. the paper Stroop

A novel digital biomarker, the interference portion of the electronic Stroop task (eStroop C), administered on a tablet to both MCI and caregivers, yielded comparable results to the interference portion of the traditional "paper" Stroop (pStroop C). Both tests were administered remotely, via videoconference as part of a baseline neuropsychological evaluation for an RCT initiated during the height of the COVID pandemic. Future clinical trials could consider adopting this self-administered digital Stroop for a comparable measure of executive function, for ease of periodic administration.