Ciclosonide reduces lipid droplet burden in APOE4 astrocytes

These findings enhance understanding of LD formation and isoform-specific differences in astrocytes. Given the role of LDs in AD, these insights may contribute to understanding AD pathogenesis and identifying therapeutic strategies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_102039
Primary Topic
Lipid metabolism and biosynthesis
Type
article
Field-Weighted Citation Impact
0.00
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article

Ciclosonide reduces lipid droplet burden in APOE4 astrocytes

Jasmine Phénix, M. Navarro Hernandez, Nicolas Audet, Antonio Vázquez Cobá et al.
Alzheimer s & Dementia
Lipid metabolism and biosynthesis
article

Ciclosonide reduces lipid droplet burden in APOE4 astrocytes

Jasmine Phénix, M. Navarro Hernandez, Nicolas Audet, Antonio Vázquez Cobá, Dongwei Yu, Sarah Anna Lisa Zünd, Lisa Marie Munter
article en

Abstract

These findings enhance understanding of LD formation and isoform-specific differences in astrocytes. Given the role of LDs in AD, these insights may contribute to understanding AD pathogenesis and identifying therapeutic strategies.

Alzheimer s & DementiaVol. 21(S5)
Munich University of Applied Sciences (DE), Frauenklinik der Technischen Universität München (DE), McGill University (CA), Technical University of Munich (DE)
Good health and well-being
Openalex Percentile: Top 32%
Lipid metabolism and biosynthesis
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