The current state of the screening and enrollment pipeline for clinical research engagement in the era of disease modifying therapies for Alzheimer’s disease
This data suggests that increasing the pipeline of potential research participants for clinical trials should focus on continued efforts to destigmatize clinical trial engagement, adapt inclusion/exclusion criteria to allow concomitant disease-modifying therapies, and eliminate unnecessary exclusion criteria if it does not affect safety and or primary outcome measures.
Authors
- A. G. Shaffer
- Gregory A. Jicha (ORCID: https://orcid.org/0000-0002-7980-2166)
- Alexandra Curtis (ORCID: https://orcid.org/0000-0002-6742-062X)
- Laura Clewett
- Muna Amry
- M. K. Harper
- Rosmy George
- Lauren Bojarski
- Elif Coşkun
- Melanie G Elam
- Shreeya Shrestha
Institutions
- University of Kentucky (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_106302
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00