A pilot medication‐wide association study for ADRD drug repurposing using the Million Veteran Program
These findings demonstrate the robustness of the MWAS approach while highlighting new insights through the integration of genomic and SDOH data. It also underscores the potential of leveraging real-world data and explainable AI to identify candidate drugs for ADRD prevention.
Authors
- D. W. Tsuang
- MA Philip
- Atif Ahmed (ORCID: https://orcid.org/0000-0002-8791-5785)
- Edward Zamrini
- Yan Cheng
- `Qing Zeng
- Yijun Shao
- Mark W. Logue
Institutions
- Boston University (US)
- George Washington University (US)
- VA Puget Sound Health Care System (US)
- Washington DC VA Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_106801
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00