318eP Therapeutic outcomes of PD-1 vs PD-L1 inhibitors in metastatic colorectal cancer: A meta-analysis of survival and safety

Immune checkpoint inhibitors (ICIs) targeting PD-1 and PD-L1 have revolutionized the treatment of multiple solid tumors, but their relative efficacy in metastatic colorectal cancer (mCRC) remains unclear. Therefore, this study aims to compare the survival outcomes and safety of PD-1 versus PD-L1 inhibitors in mCRC using data from randomized controlled trials (RCTs).

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Publication Details

Journal
Immuno-Oncology Technology
Published
2025-12-01
DOI
https://doi.org/10.1016/j.iotech.2025.101517
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

318eP Therapeutic outcomes of PD-1 vs PD-L1 inhibitors in metastatic colorectal cancer: A meta-analysis of survival and safety

Y. Al-Sadoon, R. Al-Dulaimi, Y. Alassi, M. Al-Kubaisi et al.
Immuno-Oncology Technology
Cancer Immunotherapy and Biomarkers
article

318eP Therapeutic outcomes of PD-1 vs PD-L1 inhibitors in metastatic colorectal cancer: A meta-analysis of survival and safety

Y. Al-Sadoon, R. Al-Dulaimi, Y. Alassi, M. Al-Kubaisi, M.M. Saber, A. Shorbagi, A. Abusaqer, O. Hamodat, A. Mohamad, S. Almuzainy
article en

Abstract

Immune checkpoint inhibitors (ICIs) targeting PD-1 and PD-L1 have revolutionized the treatment of multiple solid tumors, but their relative efficacy in metastatic colorectal cancer (mCRC) remains unclear. Therefore, this study aims to compare the survival outcomes and safety of PD-1 versus PD-L1 inhibitors in mCRC using data from randomized controlled trials (RCTs).

Immuno-Oncology TechnologyVol. 28
University of Sharjah (AE)
Good health and well-being
Openalex Percentile: Top 31%
Cancer Immunotherapy and Biomarkers
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