414P Single-cell mapping links human epidermal growth factor receptor 2 (HER2) tiers to interferon loss and PPAR-driven myeloid remodeling and the tumor immune microenvironment in breast cancer

phagocytic function that merits further investigation.These findings highlight the dynamic interplay within the TME and support ongoing efforts toward macrophagetargeted immunomodulation in cancer therapy.

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Publication Details

Journal
Immuno-Oncology Technology
Published
2025-12-01
DOI
https://doi.org/10.1016/j.iotech.2025.101411
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00
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article

414P Single-cell mapping links human epidermal growth factor receptor 2 (HER2) tiers to interferon loss and PPAR-driven myeloid remodeling and the tumor immune microenvironment in breast cancer

Y. Tan, T. Shang, Z. Zhang, Q. Peng et al.
Immuno-Oncology Technology
Single-cell and spatial transcriptomics
article

414P Single-cell mapping links human epidermal growth factor receptor 2 (HER2) tiers to interferon loss and PPAR-driven myeloid remodeling and the tumor immune microenvironment in breast cancer

Y. Tan, T. Shang, Z. Zhang, Q. Peng, Y. Yu
article en

Abstract

phagocytic function that merits further investigation.These findings highlight the dynamic interplay within the TME and support ongoing efforts toward macrophagetargeted immunomodulation in cancer therapy.

Immuno-Oncology TechnologyVol. 28
Sun Yat-sen University (CN), Sun Yat-sen Memorial Hospital (CN)
Good health and well-being
Openalex Percentile: Top 36%
Single-cell and spatial transcriptomics
DOIOpen Access PDFOpenAlex
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