Endometrial cancer in a young nulliparous woman: a case report

Prolonged or irregular menstrual bleeding is common in women, particularly in the early years after menarche. Over time, menstrual cycles often become regular; however, persistently irregular menstruation warrants further investigation. Serious conditions, such as endometrial cancer, which is often linked to prolonged unopposed estrogen exposure, can be prevented with timely detection. We report a case involving a 27-year-old obese, nulliparous woman with a history of prolonged irregular menstrual bleeding since menarche. She had not undergone regular health checkups and had never been properly evaluated until multiple admissions for severe anemia prompted further investigation, which confirmed the diagnosis of endometrial carcinoma. Delays in seeking care for abnormal menstrual bleeding resulted in serious outcomes. Endometrial carcinoma may significantly reduce future fertility potential. Therefore, primary healthcare providers play a pivotal role in educating and raising public awareness about this frequently under-recognized issue, as timely investigation for early recognition is paramount.

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Publication Details

Journal
Korean Journal of Family Medicine
Published
2025-12-26
DOI
https://doi.org/10.4082/kjfm.25.0163
Primary Topic
Gynecological conditions and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Endometrial cancer in a young nulliparous woman: a case report

Engku Ismail Engku-Husna, Herfiana Mohd Rapi, Azlina Ishak, Juliawati Muhammad
Korean Journal of Family Medicine
Gynecological conditions and treatments
article

Endometrial cancer in a young nulliparous woman: a case report

Engku Ismail Engku-Husna, Herfiana Mohd Rapi, Azlina Ishak, Juliawati Muhammad
article en

Abstract

Prolonged or irregular menstrual bleeding is common in women, particularly in the early years after menarche. Over time, menstrual cycles often become regular; however, persistently irregular menstruation warrants further investigation. Serious conditions, such as endometrial cancer, which is often linked to prolonged unopposed estrogen exposure, can be prevented with timely detection. We report a case involving a 27-year-old obese, nulliparous woman with a history of prolonged irregular menstrual bleeding since menarche. She had not undergone regular health checkups and had never been properly evaluated until multiple admissions for severe anemia prompted further investigation, which confirmed the diagnosis of endometrial carcinoma. Delays in seeking care for abnormal menstrual bleeding resulted in serious outcomes. Endometrial carcinoma may significantly reduce future fertility potential. Therefore, primary healthcare providers play a pivotal role in educating and raising public awareness about this frequently under-recognized issue, as timely investigation for early recognition is paramount.

Korean Journal of Family Medicine
Universiti Sains Malaysia (MY), Hospital Universiti Sains Malaysia (MY)
Openalex Percentile: Top 26%
Gynecological conditions and treatments
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