Digital Biomarkers in Early Alzheimer's Disease from Wearables or Portables: A Scoping Review

We identified a growing source of studies investigating digital biomarkers in early AD, the only population considered eligible for anti-amyloid therapy. There was a paucity of studies examining the diagnostic and prognostic usefulness of digital biomarkers, which remains a knowledge gap in this population. Our study provides an overview to guide future research efforts to bridge the gap between development and clinical application of novel digital biomarkers in early Alzheimer's disease.