Micro and Nanoencapsulation of Omega‐3 Fatty Acids: Functional Applications and Future Perspectives in Food Systems

ABSTRACT This review critically examines the current state of whey protein‐based micro and nanoencapsulation for the delivery of omega‐3 polyunsaturated fatty acids (PUFAs) in food systems. The literature demonstrates that micro and nanoencapsulation, particularly using whey protein as a wall material, significantly enhances the oxidative stability and bioavailability of omega‐3 PUFAs, addressing key challenges related to their incorporation into functional foods. The authors highlight that while traditional encapsulation methods such as spray drying and coacervation are widely used, their limitations—especially in terms of heat sensitivity and encapsulation efficiency—necessitate the exploration of novel approaches. The review underscores the potential of emerging technologies, including electrospray and 3D‐printed carriers, to further improve encapsulation performance and targeted delivery. Additionally, the integration of sustainable materials such as whey protein aligns with industry trends toward environmental responsibility and resource valorization. Looking forward, future research should focus on overcoming the poor acid stability of whey protein, optimizing encapsulation strategies for industrial application, and developing smart delivery systems that respond to physiological triggers. These directions are essential for maximizing the health benefits and commercial viability of omega‐3‐enriched food products.

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Publication Details

Journal
Food Safety and Health
Published
2025-12-25
DOI
https://doi.org/10.1002/fsh3.70071
Citations
1
Primary Topic
Microencapsulation and Drying Processes
Type
article
Field-Weighted Citation Impact
1.16
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Micro and Nanoencapsulation of Omega‐3 Fatty Acids: Functional Applications and Future Perspectives in Food Systems

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1 citations
Food Safety and Health
Microencapsulation and Drying Processes
1.16
article

Micro and Nanoencapsulation of Omega‐3 Fatty Acids: Functional Applications and Future Perspectives in Food Systems

Osama Magouz, Beraat Özçelik, Ahmed A. Zaky, Mohamed Said Boulkrane, Fadwa W. Abdulqahar, Jihan M. Kassem, Amr Farouk, Xueming Liu, Tamer M. El‐Messery, Aya Darwish
article en
1 citations

Abstract

ABSTRACT This review critically examines the current state of whey protein‐based micro and nanoencapsulation for the delivery of omega‐3 polyunsaturated fatty acids (PUFAs) in food systems. The literature demonstrates that micro and nanoencapsulation, particularly using whey protein as a wall material, significantly enhances the oxidative stability and bioavailability of omega‐3 PUFAs, addressing key challenges related to their incorporation into functional foods. The authors highlight that while traditional encapsulation methods such as spray drying and coacervation are widely used, their limitations—especially in terms of heat sensitivity and encapsulation efficiency—necessitate the exploration of novel approaches. The review underscores the potential of emerging technologies, including electrospray and 3D‐printed carriers, to further improve encapsulation performance and targeted delivery. Additionally, the integration of sustainable materials such as whey protein aligns with industry trends toward environmental responsibility and resource valorization. Looking forward, future research should focus on overcoming the poor acid stability of whey protein, optimizing encapsulation strategies for industrial application, and developing smart delivery systems that respond to physiological triggers. These directions are essential for maximizing the health benefits and commercial viability of omega‐3‐enriched food products.

Food Safety and Health
University of Anbar (IQ), Guangdong Academy of Agricultural Sciences (CN), SDS Biotech (Japan) (JP), Agricultural Genetic Engineering Research Institute (EG), National Research Centre (EG), Teknoloji Arastirma ve Gelistirme Endustriyel Urunler Bilisim Teknolojileri San Tic (TR), Animal Health Research Institute (TW), Agricultural Research Center (EG), Istanbul Technical University (TR)
Responsible consumption and production
Openalex Percentile: Top 15%
Microencapsulation and Drying Processes
1.16
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