Declining to learn results of research biomarker tests for Alzheimer Disease
In this study of participants enrolled in a longitudinal cohort of aging offered their research results, those with a parental history of AD dementia and Black participants were significantly more likely to decline. Qualitative interviews suggest that a family history of AD can create negative experiences and perceptions of the disease, which may influence the decision to learn results. Further research is needed to better understand racial differences in uptake and ensure that the choice to receive research results reflect individual preferences and wishes.
Authors
- Spondita Goswami (ORCID: https://orcid.org/0000-0002-3359-1869)
- Amy Isobel Oliver
- Jessica Mozersky (ORCID: https://orcid.org/0000-0002-4942-4571)
- Sarah M. Hartz (ORCID: https://orcid.org/0000-0002-5429-3799)
- Erin Linnenbringer (ORCID: https://orcid.org/0000-0002-3883-0013)
- Krista L. Moulder
- Sacha Jackson
- Alissa Evans
- Tomi Ogungbenle
- John C. Morris
Institutions
- Washington University in St. Louis (US)
- Center for Practical Bioethics (US)
- Prevent Alzheimer’s Disease 2020 (US)
- Saint Louis University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70858_101067
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00