382P Beyond pathologic response: Does spontaneous tumor regression (STR) influence outcomes in resected stage IIIA-N2 non-small cell lung cancer (NSCLC)? A LungART trial substudy

In the chemoimmunotherapy era, pathological response to neoadjuvant treatment (NA) has arisen as a surrogate endpoint for survival in resectable NSCLC. However, the prognostic value of STR - described in untreated patients (pts) across multiple tumor types - remains unaddressed. We assessed the impact of viable tumor fraction (VTF) as a marker of STR in resected stage IIIA-N2 NSCLC.

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Publication Details

Journal
Immuno-Oncology Technology
Published
2025-12-01
DOI
https://doi.org/10.1016/j.iotech.2025.101568
Primary Topic
Cancer Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

382P Beyond pathologic response: Does spontaneous tumor regression (STR) influence outcomes in resected stage IIIA-N2 non-small cell lung cancer (NSCLC)? A LungART trial substudy

V.M. Albarran Artahona, JP. Dales, E. Bouvier, C. Le Pechoux et al.
Immuno-Oncology Technology
Cancer Research and Treatments
article

382P Beyond pathologic response: Does spontaneous tumor regression (STR) influence outcomes in resected stage IIIA-N2 non-small cell lung cancer (NSCLC)? A LungART trial substudy

V.M. Albarran Artahona, JP. Dales, E. Bouvier, C. Le Pechoux, M. Guckenberger, F. Morin, R. Reyes, M.R. Ghigna, V. Westeel, B. Besse, J. Remon Masip, J. Adam, A. Levy, C. Faivre-Finn, A. Lopez Gutierrez, D. Diaz-Jimenez, G. Granier, N. Cozic, W.S. Zrafi
article en

Abstract

In the chemoimmunotherapy era, pathological response to neoadjuvant treatment (NA) has arisen as a surrogate endpoint for survival in resectable NSCLC. However, the prognostic value of STR - described in untreated patients (pts) across multiple tumor types - remains unaddressed. We assessed the impact of viable tumor fraction (VTF) as a marker of STR in resected stage IIIA-N2 NSCLC.

Immuno-Oncology TechnologyVol. 28
Inserm (FR), Institut Gustave Roussy (FR), Centre Hospitalier Universitaire Henri-Mondor (FR), Centre Hospitalier Universitaire de Besançon (FR), Instituto Oncológico Dr. Rosell (ES), Intergroupe Francophone de Cancérologie Thoracique (FR), University Hospital of Zurich (CH), Hôpital Nord (FR), The Christie NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 31%
Cancer Research and Treatments
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