Factors Associated With Rare Pediatric Cancer Trial Enrollment: A Report From the Children's Oncology Group Rare Tumors Committee
Although children with rare cancers enrolled in COG studies reflect the US population, enrollment in the COG registry/biospecimen repository continues to be limited in the absence of therapeutic trials, impacting data and biospecimens available to inform therapeutic trial development. Expansion of therapeutic trials or free molecular testing through the Molecular Characterization Initiative may increase data and biospecimens for these rare cancers.
Authors
- Junne Kamihara (ORCID: https://orcid.org/0000-0002-2852-7387)
- Jin Piao
- T. Laetsch
- Sarah G. Mitchell (ORCID: https://orcid.org/0000-0003-1656-2799)
- Samara L. Poplack Potter (ORCID: https://orcid.org/0000-0001-7122-953X)
- Kenneth Chen (ORCID: https://orcid.org/0000-0003-2304-4631)
- Hetal Dholaria (ORCID: https://orcid.org/0000-0003-1713-3822)
- Michael R. Sargen (ORCID: https://orcid.org/0000-0003-1039-2522)
- Jennifer H. Aldrink (ORCID: https://orcid.org/0000-0002-6547-1220)
- Farzana Pashankar (ORCID: https://orcid.org/0000-0003-2883-0957)
- Mary Frances Frances Wedekind
- Robyn Gartrell
- Jeremy Rosenblum
- Brian R. Englum
- M. John Hicks
- Emily Christison‐Lagay
- Kris Ann P. Schultz
- Lindsay Younis
- Brittani K. N. Seynnaeve
- Manuela Orjuela‐Grimm
- Reto M. Baertschiger
Institutions
- Children's Oncology Group (CH)
- University of Maryland, Baltimore (US)
- Nationwide Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- Johns Hopkins University (US)
- University of Pittsburgh (US)
- The Kids Research Institute Australia (AU)
- New York Medical College (US)
- Baylor College of Medicine (US)
- Columbia University Irving Medical Center (US)
- Johns Hopkins Medicine (US)
- Princess Margaret Hospital for Children (AU)
- Yale University (US)
- Children's Minnesota (US)
- Children's Oncology Group (US)
- National Cancer Institute (US)
- Children's Hospital at Dartmouth Hitchcock (US)
- Children's Healthcare of Atlanta (US)
- Texas Children's Hospital (US)
- Department of Health and Human Services (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- The Ohio State University (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1002/pbc.32164
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Cancer Institute
- National Center for Advancing Translational Sciences