Decreased plasma platelet‐derived growth factor receptor‐β correlates with β‐amyloid, tau, and cognitive decline in male Alzheimer's disease
These findings demonstrated that decreased plasma PDGFRβ levels are related to BBB damage, providing a potential plasma biomarker to detect and monitor BBB leakage in AD, particularly in males.
Authors
- Laihong Zhang
- Guoyu Lan (ORCID: https://orcid.org/0000-0003-2925-1738)
- Xuhui Chen (ORCID: https://orcid.org/0000-0002-2660-7666)
- Dai Shi
- Jie Yang (ORCID: https://orcid.org/0000-0003-4346-9100)
- Zhen Liu (ORCID: https://orcid.org/0000-0002-4645-1179)
- Shaohua Ma (ORCID: https://orcid.org/0000-0003-4995-6938)
- Jieyin Li
- Tengfei Guo
- Anqi Li
Institutions
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Shenzhen Bay Laboratory (CN)
- Tsinghua–Berkeley Shenzhen Institute (CN)
- Peking University Shenzhen Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101847
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00