Detecting Pathology‐Confirmed Neurodegenerative Patterns in Mixed‐Dementia: Deep Learning Networks Construct Novel Neuroimaging Signatures of Alzheimer's, Vascular, and Lewy Body Dementias

We have demonstrated the effectiveness of our novel deep-learning framework in identifying antemortem neuroimaging signatures associated with distinct pathologies. The newly developed DeepSPARE indices are accurate, pathology-specific, and noninvasive neuroimaging metrics, connecting widely available in-vivo T1 imaging with pathological identifications.