Peri-device leak and late massive thrombus formation after left atrial appendage occlusion: A case report

Even minimal PDL can serve as a nidus for significant late thrombus formation, particularly in patients with interrupted anticoagulation. This case highlights the importance of continued long-term imaging surveillance after LAAO and individualized anticoagulation strategies. Clinicians should maintain vigilance for late DRT, especially in high-risk patients, and consider extended follow-up protocols to optimize outcomes.