ALyzer3D.AI: a more generalizable deep learning predictor of light chain amyloidogenicity powered by structural and evolutionary Artificial Intelligence

ALyzer3D.AI provides a robust, interpretable tool for predicting light-chain amyloidogenicity that generalizes better to independent datasets than existing methods. It is publicly available <i>via</i> https://colab.research.google.com/github/pcmay/ALyzer3D.AI/blob/main/ALyzer3DAI.ipynb.

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Publication Details

Journal
Amyloid
Published
2025-12-25
DOI
https://doi.org/10.1080/13506129.2025.2605534
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

ALyzer3D.AI: a more generalizable deep learning predictor of light chain amyloidogenicity powered by structural and evolutionary Artificial Intelligence

Marion Högner, Peter May, Florian Bassermann, Johannes Jung
Amyloid
Alzheimer's disease research and treatments
article

ALyzer3D.AI: a more generalizable deep learning predictor of light chain amyloidogenicity powered by structural and evolutionary Artificial Intelligence

Marion Högner, Peter May, Florian Bassermann, Johannes Jung
article en

Abstract

ALyzer3D.AI provides a robust, interpretable tool for predicting light-chain amyloidogenicity that generalizes better to independent datasets than existing methods. It is publicly available <i>via</i> https://colab.research.google.com/github/pcmay/ALyzer3D.AI/blob/main/ALyzer3DAI.ipynb.

Amyloid
Technical University of Munich (DE)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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