Large Language Model for Predicting Altered Mental Status in Dementia Patients Using Electronic Health Records

This study demonstrates the potential of using EHRs and LLMs to predict altered mental status in dementia patients. The LLMs showed fine predictive performance, while the CoT strategy provided enhanced interpretability at the cost of reduced accuracy. These findings emphasize the need to optimize LLM in clinical applications and highlight the promise of advanced AI tools in improving dementia care through efficient risk assessment and timely interventions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70858_104165
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
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article

Large Language Model for Predicting Altered Mental Status in Dementia Patients Using Electronic Health Records

Richard Wyss, Jiageng Wu, Josh C. H. Lin, Jie Yang
Alzheimer s & Dementia
Machine Learning in Healthcare
article

Large Language Model for Predicting Altered Mental Status in Dementia Patients Using Electronic Health Records

Richard Wyss, Jiageng Wu, Josh C. H. Lin, Jie Yang
article en

Abstract

This study demonstrates the potential of using EHRs and LLMs to predict altered mental status in dementia patients. The LLMs showed fine predictive performance, while the CoT strategy provided enhanced interpretability at the cost of reduced accuracy. These findings emphasize the need to optimize LLM in clinical applications and highlight the promise of advanced AI tools in improving dementia care through efficient risk assessment and timely interventions.

Alzheimer s & DementiaVol. 21(S4)
Brigham and Women's Hospital (US)
Openalex Percentile: Top 18%
Machine Learning in Healthcare
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Large Language Model for Predicting Altered Mental Status in Dementia Patients Using Electronic Health Records — Richard Wyss, Jiageng Wu, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS