Potential Eligibility for Lecanemab in a Cohort of Alzheimer’s Dementia Patients from India

A substantial proportion (80.75%) of dementia patients from LMICs may be ineligible for lecanemab due to diagnostic and resource limitations. However, 20.8% of clinically diagnosed AD could potentially be eligible with biomarker testing. Efforts to enhance biomarker availability, early detection, and cost-effective strategies are crucial to enable equitable access to emerging AD therapies in LMICs.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_106469
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Potential Eligibility for Lecanemab in a Cohort of Alzheimer’s Dementia Patients from India

Suvarna Alladi, Sivasubramanian Ramakrishnan, P Sastry, Mahammad Samim Mondal et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Potential Eligibility for Lecanemab in a Cohort of Alzheimer’s Dementia Patients from India

Suvarna Alladi, Sivasubramanian Ramakrishnan, P Sastry, Mahammad Samim Mondal, Sarath Govindaraj, S Sandeep Kumar, Faheem Arshad
article en

Abstract

A substantial proportion (80.75%) of dementia patients from LMICs may be ineligible for lecanemab due to diagnostic and resource limitations. However, 20.8% of clinically diagnosed AD could potentially be eligible with biomarker testing. Efforts to enhance biomarker availability, early detection, and cost-effective strategies are crucial to enable equitable access to emerging AD therapies in LMICs.

Alzheimer s & DementiaVol. 21(S5)
National Institute of Mental Health and Neurosciences (IN)
Reduced inequalities
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
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