Recombinant Listeria expressing the HPV multivalent E6E7 protein has a broader spectrum of anti-tumor effects against cervical cancer
Our objective was to evaluate the efficacy of the vaccine against subcutaneous HPV16/18 E6/E7-expressing tumor models, enhance its safety profile, and co-express multivalent HPV antigens to target a broader range of cervical cancer types.
Authors
- Qian Ou
- Zinan Chen
- Zhaobin Chen
- Sihan Qin
- Shanping Gan
- Chuan Wang
- Jing Tang
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Viva Biotech (China) (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1186/s12885-025-15476-z
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00