Plasma protein‐based organ age gap and pace of organ aging were associated with incident dementia and brain structures
Older age gaps and faster pace of aging in organs other than the brain, e.g., heart, immune system, and pancreas, may play an important role in dementia risk and structural brain changes.
Authors
- Jingsha Chen
- Basilio Cieza
- Jarod Rutledge (ORCID: https://orcid.org/0000-0001-7790-2801)
- Ramon Casanova (ORCID: https://orcid.org/0000-0002-6934-5942)
- Wenyu Zhou (ORCID: https://orcid.org/0000-0002-8447-8815)
- Hamilton Se‐Hwee Oh (ORCID: https://orcid.org/0000-0001-8192-7593)
- Michael R. Duggan (ORCID: https://orcid.org/0000-0002-1029-4423)
- Gricelda Gómez
- Keenan A. Walker (ORCID: https://orcid.org/0000-0002-5989-9853)
- Shuo M. Wang
- MORGAN GRAMS
- Fangyu Liu (ORCID: https://orcid.org/0000-0003-1554-1478)
- Cassandra M Joynes
- Tony Wyss‐Coray
- Alex Boches
- Sanaz Sedaghat
- Aditya Surapaneni
- Anna Prizment
- Josef Coresh
- Michael E. Griswold
Institutions
- Brigham and Women's Hospital (US)
- University of Minnesota (US)
- Johns Hopkins University (US)
- Neurosciences Institute (US)
- Jackson Memorial Hospital (US)
- University of Mississippi Medical Center (US)
- Tesla (United States) (US)
- National Institute on Aging (US)
- Wake Forest University (US)
- New York University (US)
- Columbia University (US)
- Stanford University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100937
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00