High E2F7 Expression Indicates Pancreatic Cancer Aggressiveness and Downregulation of E2F7 Enhances Sensitivity to S-1
Tissue mRNA expression levels of E2F7 correlated with patient prognosis in PC. In the low E2F7 mRNA expression group, patients who received S-1 as adjuvant chemotherapy had a better prognosis than those who received gemcitabine (GEM).
Authors
- Atsuyuki MAEDA
- Katsuhiko Uesaka (ORCID: https://orcid.org/0000-0002-9983-1730)
- Atsushi Enomoto (ORCID: https://orcid.org/0000-0002-4149-6247)
- Naoto YAMAMOTO
- Motokazu SUGIMOTO
- Keizo Fujita (ORCID: https://orcid.org/0000-0003-4111-9852)
- Yukihiro Yokoyama (ORCID: https://orcid.org/0000-0003-2385-5610)
- Junpei Yamaguchi (ORCID: https://orcid.org/0000-0002-5892-5271)
- Nobumasa Mizuno (ORCID: https://orcid.org/0000-0001-9704-1885)
- Shinji Mii (ORCID: https://orcid.org/0000-0001-8266-3235)
- Akihiro Sakai (ORCID: https://orcid.org/0000-0002-8552-2179)
- Hideki Takami
- Yukiyasu Okamura
- Haruyoshi Tanaka
- Nobuhiko Nakagawa
- Masamichi Hayashi
- Mitsuro Kanda
- Tomohisa Otsu
- Hirochika Toyama
- Ryo Ashida
- Keisuke Kurimoto
Institutions
- Nihon University (JP)
- Hiroshima University (JP)
- Kanagawa Prefectural Hospital Organization (JP)
- Shizuoka Cancer Center (JP)
- Ogaki Municipal Hospital (JP)
- Aichi Cancer Center (JP)
- National Cancer Center Hospital East (JP)
- Kanagawa Cancer Center
- Nagoya University (JP)
- Kobe University (JP)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1245/s10434-025-18912-3
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05