Impact of ketosis on neuronal activity: a characterization of the functional role of ketone bodies using non‐invasive encephalography in humans
The ketogenic diet enhances neuronal aperiodic 1/f activity by providing a fast and alternative energy source in the form of ketone bodies. These findings suggest potential therapeutic applications for aging and neurodegenerative disorders for ketogenic interventions and suggest a key modulation of the central nervous system, likely involving astrocyte-neuron pathway. Authors: Felipe González*, Daniel Franco-O'Byrne*, Ana María Castro-Laguardia, Tomás Bosch, Tomás Ossandón, Vicente Medel *=equally contributing authors °=corresponding author Funding: FONDECYT Exploración 13240170 and FONDECYT de Iniciación 11251578.
Authors
- Vicente Medel (ORCID: https://orcid.org/0000-0003-2443-8683)
- Daniel Franco O'Byrne
- Felipe Ignacio González Henríquez
Institutions
- Pontificia Universidad Católica de Chile (CL)
- Adolfo Ibáñez University (CL)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103513
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00