Impact of antimicrobial prophylaxis in colorectal cancer surgery on the gut and oral microbiome and resistome: A prospective observational cohort study
Oral and gut microbiomes and resistomes exhibited marked alterations that gradually reversed over time. Changes in the microbiome were associated with the spectrum of antibiotics used.
Authors
- Hirofumi Doi (ORCID: https://orcid.org/0000-0003-3829-2726)
- Toshiki Kajihara (ORCID: https://orcid.org/0000-0002-7576-2654)
- Motoyuki Sugai (ORCID: https://orcid.org/0000-0001-9252-7739)
- Hitoshi KOMATSUZAWA
- Norifumi Shigemoto (ORCID: https://orcid.org/0000-0001-9069-463X)
- Ikki Nakashima
- Norikazu Kitamura (ORCID: https://orcid.org/0009-0006-3738-3545)
- Hiroki Kitagawa (ORCID: https://orcid.org/0000-0003-1651-0091)
- Shinnosuke Uegami
- Hiroki Ohge
- Koji Yahara
- Kosuke Yoshimura
- Miki Kawada-Matsuo
- Yusuke Watadani
- Kensuke Shimbara
Institutions
- Hiroshima University (JP)
- National Institute of Infectious Diseases (JP)
- Hiroshima University Hospital (JP)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1016/j.jgar.2025.12.014
- Primary Topic
- Surgical site infection prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00