Short‐interval common game play distinguishes people with and without cognitive impairment

Nine of ten features differentiated normal cognition [NCC/SCD] from impairment [MCI/MD], with CI participants performing worse across features [Figure 1] Percent Accuracy displays a high correlation with RBANs Immediate & Delayed Memory Indices [r = 0.60 to 0.75]. Similarly, Number of Hard Drops exhibits a strong association with TMT A & B [r = -0.61 to -0.71], while Word Score demonstrates a moderate association with RBANs Language Index [r = 0.5] [Table 1.] CONCLUSION: Features of the MIND GamePack^© effectively differentiate CN from CI individuals over a short period with digital biomarkers highlighting memory, language, and executive function differences. Gamified assessments can be incorporated into clinical trials to facilitate screening, track performance over time, and may serve as sensitive measures of cognitive stability, decline, or response.