IK‐5f targets amyloid aggregates and alleviates cognitive deficits in the 5XFAD Alzheimer mouse model
IK-5f exhibits strong potential as a small-molecule drug candidate for AD by effectively reducing Aβ pathology and neuroinflammation while enhancing cognitive function.
Authors
- Illhwan Cho
- Suhyun Ye
- Soljee Yoon (ORCID: https://orcid.org/0000-0002-5063-8921)
- Seok Hyun Yoon (ORCID: https://orcid.org/0000-0002-2011-0800)
- Heewon Shin
- Ikyon Kim (ORCID: https://orcid.org/0000-0002-0849-5517)
- Songmin Lee (ORCID: https://orcid.org/0009-0006-3585-1261)
- InWook Park
- YoungSoo Kim
- Sunhee Lee
Institutions
- Incheon National University (KR)
- Yonsei University (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_101506
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00