Ageing and Neurodegeneration: A Study of Plasma Biomarkers and Neuroimage in a Brazilian Cohort
Plasma NfL is a promising biomarker for neurodegenerative changes, showing strong correlations with aging and brain volume reductions in gray matter, white matter, hippocampus, and cortical thickness. Establishing reference values for the Brazilian population is essential for clinical application, supporting its use in diagnosing and monitoring neurodegenerative diseases.
Authors
- Ivanei E. Bramati (ORCID: https://orcid.org/0000-0001-8721-9053)
- Felipe Kenji Sudo (ORCID: https://orcid.org/0000-0003-4738-1368)
- Débora Afonso Silva Rocha
- Fernanda Guarino De Felice
- Fernanda Tovar‐Moll
- Andrea Silveira Souza
- Luis E. Santos
- Thaís Lopes Pinheiro
- Paulo E. Mattos
- Fernanda Hansen
Institutions
- Queen's University (CA)
- D’Or Institute for Research and Education (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102923
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00