Microstructural differences in white matter tracts in Alzheimer's disease, cerebrovascular disease, and Parkinson's disease

PD participants had slightly more preserved white matter tract microstructural integrity than ADMCI or CVD participants who had lower FA and higher RD and MD values. Higher-quality, advanced diffusion imaging may be necessary to detect the more subtle changes in white matter microstructure present in Parkinson's disease patients.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_104478
Primary Topic
Advanced Neuroimaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Microstructural differences in white matter tracts in Alzheimer's disease, cerebrovascular disease, and Parkinson's disease

Robert Bartha, Dana N Broberg, ONDRI Investigators, Angela C. Roberts et al.
Alzheimer s & Dementia
Advanced Neuroimaging Techniques and Applications
article

Microstructural differences in white matter tracts in Alzheimer's disease, cerebrovascular disease, and Parkinson's disease

Robert Bartha, Dana N Broberg, ONDRI Investigators, Angela C. Roberts, Richard H. Swartz, Sandra E. Black, Anthony E Lang
article en

Abstract

PD participants had slightly more preserved white matter tract microstructural integrity than ADMCI or CVD participants who had lower FA and higher RD and MD values. Higher-quality, advanced diffusion imaging may be necessary to detect the more subtle changes in white matter microstructure present in Parkinson's disease patients.

Alzheimer s & DementiaVol. 21(S2)
Western University (CA), University of Toronto (CA), Toronto Western Hospital (CA), Robarts Clinical Trials (CA), Sunnybrook Hospital (CA), Sunnybrook Research Institute
Openalex Percentile: Top 31%
Advanced Neuroimaging Techniques and Applications
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Microstructural differences in white matter tracts in Alzheimer's disease, cerebrovascular disease, and Parkinson's disease — Robert Bartha, Dana N Broberg, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS