Comparison of left ventricular diastolic function parameters in patients induced with propofol and etomidate: A randomized clinical trial

This study found that anaesthesia induction with propofol and etomidate in adults resulted in a statistically significant decrease in E-wave, septal, and lateral e' velocities within the groups. The reduction in E-wave velocity caused by etomidate was more profound when compared with propofol. While both propofol and etomidate may mildly worsen certain parameters of diastolic function, this study did not demonstrate any worsening of diastolic parameters like LAVI, TRVmax, and E/e'.

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Publication Details

Journal
Journal of Anaesthesiology Clinical Pharmacology
Published
2025-12-26
DOI
https://doi.org/10.4103/joacp.joacp_73_25
Primary Topic
Anesthesia and Sedative Agents
Type
article
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article

Comparison of left ventricular diastolic function parameters in patients induced with propofol and etomidate: A randomized clinical trial

Muthapillai Senthilnathan, Sandeep Kumar Mishra, Parida Satyen, S. Suganya et al.
Journal of Anaesthesiology Clinical Pharmacology
Anesthesia and Sedative Agents
article

Comparison of left ventricular diastolic function parameters in patients induced with propofol and etomidate: A randomized clinical trial

Muthapillai Senthilnathan, Sandeep Kumar Mishra, Parida Satyen, S. Suganya, Mekala Ranjith Kumar, Shanmugappriya Arunachalam
article en

Abstract

This study found that anaesthesia induction with propofol and etomidate in adults resulted in a statistically significant decrease in E-wave, septal, and lateral e' velocities within the groups. The reduction in E-wave velocity caused by etomidate was more profound when compared with propofol. While both propofol and etomidate may mildly worsen certain parameters of diastolic function, this study did not demonstrate any worsening of diastolic parameters like LAVI, TRVmax, and E/e'.

Journal of Anaesthesiology Clinical PharmacologyVol. 42(1)
Sri Venkateshwaraa Medical College Hospital and Research Centre (IN), Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Openalex Percentile: Top 26%
Anesthesia and Sedative Agents
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