Analyzing the Effect of ACP‐204 on the QTc Interval in Healthy Adult Participants Using Phase 1 Study Data

No meaningful increases in QTcF were observed in healthy participants after single-dose administration of ACP-204 (10-180 mg); specifically, there was no QTcF prolongation up to 180 mg.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_105893
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
Field-Weighted Citation Impact
0.00
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article

Analyzing the Effect of ACP‐204 on the QTc Interval in Healthy Adult Participants Using Phase 1 Study Data

Jay W. Mason, Bryan Dirks, Mona Darwish, Sanjeev Pathak et al.
Alzheimer s & Dementia
Cardiac electrophysiology and arrhythmias
article

Analyzing the Effect of ACP‐204 on the QTc Interval in Healthy Adult Participants Using Phase 1 Study Data

Jay W. Mason, Bryan Dirks, Mona Darwish, Sanjeev Pathak, B. Raether, Stephanie W Stanworth, Xiaoshu Feng
article en

Abstract

No meaningful increases in QTcF were observed in healthy participants after single-dose administration of ACP-204 (10-180 mg); specifically, there was no QTcF prolongation up to 180 mg.

Alzheimer s & DementiaVol. 21(S5)
Acadia Pharmaceuticals (United States) (US), RED Consulting (Norway) (NO)
Good health and well-being
Openalex Percentile: Top 31%
Cardiac electrophysiology and arrhythmias
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