Identification of Mild Cognitive Impairment with Traditional, Process, and Acoustic Metrics Derived from the Digital Assessment of Cognition

The brief, iPad-administered rDAC shows promise as a tool sensitive for flagging emergent CI, on par with neuropsychological testing. We believe the combination of traditional neuropsychological outcome measures, process metrics, and acoustic features will detect the subtle performance differences that distinguish CI in real world applications.

Authors

Karl M. Thompson (ORCID: https://orcid.org/0000-0001-6182-9507)
Connor Higgins
Tanya Talkar (ORCID: https://orcid.org/0000-0002-1999-6843)
Daniel Schulman (ORCID: https://orcid.org/0000-0002-2287-7888)
David J. Libon
Sean Tobyne
Alvaro Pascual‐Leone

Institutions

Harvard University (US)
Hebrew SeniorLife (US)
Rowan University (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2025-12-01
DOI: https://doi.org/10.1002/alz70856_103763
Primary Topic: Dementia and Cognitive Impairment Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Identification of Mild Cognitive Impairment with Traditional, Process, and Acoustic Metrics Derived from the Digital Assessment of Cognition

Karl M. Thompson, Connor Higgins, Tanya Talkar, Daniel Schulman et al.

Dec 1, 2025

Alzheimer s & Dementia

Dementia and Cognitive Impairment Research

article

Identification of Mild Cognitive Impairment with Traditional, Process, and Acoustic Metrics Derived from the Digital Assessment of Cognition

Karl M. Thompson, Connor Higgins, Tanya Talkar, Daniel Schulman, David J. Libon, Sean Tobyne, Alvaro Pascual‐Leone

December 1, 2025article en

Abstract

The brief, iPad-administered rDAC shows promise as a tool sensitive for flagging emergent CI, on par with neuropsychological testing. We believe the combination of traditional neuropsychological outcome measures, process metrics, and acoustic features will detect the subtle performance differences that distinguish CI in real world applications.

Alzheimer s & DementiaVol. 21(S2)

Harvard University (US), Hebrew SeniorLife (US), Rowan University (US)

Reduced inequalities

Openalex Percentile: Top 33%

Dementia and Cognitive Impairment Research

DOI Open Access PDF OpenAlex

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Identification of Mild Cognitive Impairment with Traditional, Process, and Acoustic Metrics Derived from the Digital Assessment of Cognition — Karl M. Thompson, Connor Higgins, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS