When subarachnoid hemorrhage mimics acute coronary syndrome in out-of-hospital cardiac arrest: a diagnostic challenge

Out-of-hospital cardiac arrest (OHCA) is most often due to acute coronary syndrome (ACS), but less frequent causes like subarachnoid hemorrhage (SAH) may mimic cardiac disease through ECG changes and biomarker elevation, risking misdiagnosis and inappropriate interventions. The aim of this case was to present a case of a patient who experienced OHCA due to subarachnoid hemorrhage mimicking ACS leading to catastrophic results. A 42-year-old woman with no cardiovascular risk factors suffered sudden cardiac arrest during exercise. Initial ECG and troponin levels suggested SCA, but coronary angiography was normal. Subsequent head CT revealed a massive subarachnoid hemorrhage. Despite supportive care, the patient died on day 5 from cerebral edema. SAH can cause cardiac arrest with ECG changes mimicking ACS, highlighting the importance of cranial CT in comatose post–cardiac arrest patients.

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Publication Details

Journal
International Journal of Emergency Medicine
Published
2025-12-26
DOI
https://doi.org/10.1186/s12245-025-01106-9
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
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When subarachnoid hemorrhage mimics acute coronary syndrome in out-of-hospital cardiac arrest: a diagnostic challenge

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When subarachnoid hemorrhage mimics acute coronary syndrome in out-of-hospital cardiac arrest: a diagnostic challenge

Ali Chaib, Jihane Fagouri, Jamal Kheyi, Jaouad Nguadi, A. Benyass, Z. Lakhal, Youssef Lahmouz, Hicham Bouzelmat, Meryem Bennani, Abdelilah Ben EL Makki, Hanae EL Ghiati
article en

Abstract

Out-of-hospital cardiac arrest (OHCA) is most often due to acute coronary syndrome (ACS), but less frequent causes like subarachnoid hemorrhage (SAH) may mimic cardiac disease through ECG changes and biomarker elevation, risking misdiagnosis and inappropriate interventions. The aim of this case was to present a case of a patient who experienced OHCA due to subarachnoid hemorrhage mimicking ACS leading to catastrophic results. A 42-year-old woman with no cardiovascular risk factors suffered sudden cardiac arrest during exercise. Initial ECG and troponin levels suggested SCA, but coronary angiography was normal. Subsequent head CT revealed a massive subarachnoid hemorrhage. Despite supportive care, the patient died on day 5 from cerebral edema. SAH can cause cardiac arrest with ECG changes mimicking ACS, highlighting the importance of cranial CT in comatose post–cardiac arrest patients.

International Journal of Emergency MedicineVol. 19(1)
Mohammed V University (MA)
Good health and well-being
Openalex Percentile: Top 26%
Cardiac Arrest and Resuscitation
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