Brain‐Wide Measurement of Antibody Therapeutic Biodistribution and Target Engagement

These data provide a clear demonstration of the utility of tissue clearing methods for quantitative brain-wide monitoring of Alzheimer's Disease therapeutic antibody biodistribution.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_103765
Primary Topic
Barrier Structure and Function Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Brain‐Wide Measurement of Antibody Therapeutic Biodistribution and Target Engagement

Yessenia Gallegos, Sandra Vergo, Chase Redd, Nathaniel Guanzon et al.
Alzheimer s & Dementia
Barrier Structure and Function Studies
article

Brain‐Wide Measurement of Antibody Therapeutic Biodistribution and Target Engagement

Yessenia Gallegos, Sandra Vergo, Chase Redd, Nathaniel Guanzon, Damian G. Wheeler, Camilla Stampe Jensen
article en

Abstract

These data provide a clear demonstration of the utility of tissue clearing methods for quantitative brain-wide monitoring of Alzheimer's Disease therapeutic antibody biodistribution.

Alzheimer s & DementiaVol. 21(S5)
Lundbeck (Denmark) (DK)
Openalex Percentile: Top 38%
Barrier Structure and Function Studies
DOIOpen Access PDFOpenAlex
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Brain‐Wide Measurement of Antibody Therapeutic Biodistribution and Target Engagement — Yessenia Gallegos, Sandra Vergo, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS