Identifying a combination of biomarkers to predict treatment response to nabilone for the treatment of agitation in Alzheimer's disease – a secondary analysis

Participants with higher levels of inflammation, oxidative stress, and cholesterol metabolite were more likely to benefit from nabilone for agitation in AD. A combination of biomarkers could help in distinguishing responders and non-responders to nabilone.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_103580
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Identifying a combination of biomarkers to predict treatment response to nabilone for the treatment of agitation in Alzheimer's disease – a secondary analysis

Ana C. Andreazza, Alex Kiss, Hui Jue Wang, Krista L. Lanctôt et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Identifying a combination of biomarkers to predict treatment response to nabilone for the treatment of agitation in Alzheimer's disease – a secondary analysis

Ana C. Andreazza, Alex Kiss, Hui Jue Wang, Krista L. Lanctôt, Oriel J. Feldman, Nicolaas Paul L.G. Verhoeff, Myuri Ruthirakuhan, Nathan Herrmann, Damien Gallagher, Sandra E. Black
article en

Abstract

Participants with higher levels of inflammation, oxidative stress, and cholesterol metabolite were more likely to benefit from nabilone for agitation in AD. A combination of biomarkers could help in distinguishing responders and non-responders to nabilone.

Alzheimer s & DementiaVol. 21(S3)
Sunnybrook Health Science Centre (CA), Centre for Addiction and Mental Health (CA), University of Toronto (CA), Health Sciences Centre (CA), Baycrest Hospital (CA), Sunnybrook Hospital (CA), Sunnybrook Research Institute
Good health and well-being
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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Identifying a combination of biomarkers to predict treatment response to nabilone for the treatment of agitation in Alzheimer's disease – a secondary analysis — Ana C. Andreazza, Alex Kiss, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS