Sophocarpine Alleviates Testicular Ischemia–Reperfusion Injury by Modulating Ferroptosis via the AKT Pathway in Rats
Sophocarpine effectively protects the bilateral testes after unilateral testicular torsion-detorsion, with protective effects through ferroptosis mediated by the AKT signaling pathway, highlighting its potential as a therapeutic target in testicular IRI.
Authors
- H. Song
- Shu Wei (ORCID: https://orcid.org/0000-0001-7788-7154)
- Junshen Xiao (ORCID: https://orcid.org/0009-0009-4879-5600)
- Zhaoyang Hu
- Ting Zou
- Yun Qing
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Andrology
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1111/andr.70163
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00