Delayed recall predicts change in cerebrospinal fluid biomarkers over two years
These findings support the hypothesis that neuropsychological test performance, specifically delayed recall, is sensitive to a two-year change in some Alzheimer's disease biomarkers while other biomarkers predict change in neuropsychological test performance. Therefore, delayed recall tasks may be practical screening tests for early intervention studies to identify persons at high risk for AD while other biomarkers can predict decline in memory.
Authors
- Frank P. DiFilippo (ORCID: https://orcid.org/0000-0003-2594-7228)
- Lynn M. Bekris (ORCID: https://orcid.org/0000-0002-2747-7672)
- Maria Khrestian (ORCID: https://orcid.org/0000-0002-1621-4711)
- Stephen M. Rao
- Sally Durgerian
- Kristy A. Nielson
- Bradley J. Dixon
- J. Carson Smith
- John L. Woodard
Institutions
- Marquette University (US)
- Cleveland Clinic (US)
- Wayne State University (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_106534
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00