Do males and females show distinct symptoms in Alzheimer's disease and behavioral variant frontotemporal dementia?

These findings reveal sex-related differences in the presentation of behavioral and cognitive symptoms in AD, with females displaying more executive deficits, and males exhibiting more behavioral disturbances. These differences may contribute to diagnostic misclassification, particularly in females with atypical bvFTD-like symptoms. Improved recognition of sex-related symptom variability is crucial for enhancing diagnostic accuracy and ensuring appropriate clinical management.