Adufab‐TAT Conjugate: A Novel Approach for Transferrin Receptor‐Mediated BBB Transport in Alzheimer's Disease

The Adufab-TAT-(GGGGS)₄ conjugate shows strong binding to the transferrin receptor, with potential for enhanced blood-brain barrier penetration. This strategy could improve Alzheimer's disease treatment. Future research should validate its effectiveness through experimental assays and in vivo models to confirm its therapeutic potential.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_107662
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Adufab‐TAT Conjugate: A Novel Approach for Transferrin Receptor‐Mediated BBB Transport in Alzheimer's Disease

Moaz Elsayed Sayed Ahmed
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Adufab‐TAT Conjugate: A Novel Approach for Transferrin Receptor‐Mediated BBB Transport in Alzheimer's Disease

Moaz Elsayed Sayed Ahmed
article en

Abstract

The Adufab-TAT-(GGGGS)₄ conjugate shows strong binding to the transferrin receptor, with potential for enhanced blood-brain barrier penetration. This strategy could improve Alzheimer's disease treatment. Future research should validate its effectiveness through experimental assays and in vivo models to confirm its therapeutic potential.

Alzheimer s & DementiaVol. 21(S5)
University of Hertfordshire (GB)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
DOIOpen Access PDFOpenAlex
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Adufab‐TAT Conjugate: A Novel Approach for Transferrin Receptor‐Mediated BBB Transport in Alzheimer's Disease — Moaz Elsayed Sayed Ahmed · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS