MEG Highlights Abnormal Neural Transitions in Lewy Body Dementia
Our findings reveal distinct LBD-specific spectral slowing and dynamic connectivity patterns, characterized by prolonged engagement in temporal-prefrontal networks and reduced involvement in temporo-occipito-parietal regions. These alterations strongly correlate with cognitive fluctuations, suggesting potential biomarkers for LBD. Future research should explore targeting these abnormal state transitions to mitigate cognitive fluctuations.
Authors
- Hojjatollah Sadeqi
- Rachael M. Burke (ORCID: https://orcid.org/0000-0002-2156-5030)
- Zohreh Morshedizad
- Abbas Babajani‐Feremi
- Babak Ahmadi
- Melissa J. Armstrong
Institutions
- University of Florida (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70858_106084
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00