Organic Radicals for Tumor Therapy

Organic radical materials have emerged as promising candidates for tumor therapy, owing to their distinctive open-shell electronic structures and superior photophysical characteristics. Through chemical modifications and nanotechnological approaches, these materials have paved the way for precision medicine, showcasing robust spin-coupling phenomena and near-infrared light absorption properties. Leveraging these attributes, organic radicals have demonstrated enhanced therapeutic outcomes in photothermal therapy, photodynamic therapy, and other novel modalities. This review provides an overview of the applications of organic radicals in tumor therapy and also highlights existing hurdles and future prospects of organic radicals in cancer treatment.

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Publication Details

Journal
Langmuir
Published
2025-12-26
DOI
https://doi.org/10.1021/acs.langmuir.5c05143
Primary Topic
Nanoplatforms for cancer theranostics
Type
article
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article

Organic Radicals for Tumor Therapy

Wanlan Yang, Xuezhong Du
Langmuir
Nanoplatforms for cancer theranostics
article

Organic Radicals for Tumor Therapy

Wanlan Yang, Xuezhong Du
article en

Abstract

Organic radical materials have emerged as promising candidates for tumor therapy, owing to their distinctive open-shell electronic structures and superior photophysical characteristics. Through chemical modifications and nanotechnological approaches, these materials have paved the way for precision medicine, showcasing robust spin-coupling phenomena and near-infrared light absorption properties. Leveraging these attributes, organic radicals have demonstrated enhanced therapeutic outcomes in photothermal therapy, photodynamic therapy, and other novel modalities. This review provides an overview of the applications of organic radicals in tumor therapy and also highlights existing hurdles and future prospects of organic radicals in cancer treatment.

LangmuirVol. 42(1)
Nanjing University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Nanoplatforms for cancer theranostics
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