Sex Differences in Cognitive Reserve: Findings from a Brief Questionnaire in Biologically Confirmed Alzheimer's Disease
Cognitive reserve, which moderates the relationship between brain pathology and cognitive outcomes, may be influenced by sex. Developing feasible cognitive reserve assessments applicable to illiterate individuals, which also account for sex differences, is essential. Women may have lower cognitive reserve, particularly in populations with a high prevalence of illiteracy. Future studies are needed to explore the sex-specific moderating effects of AD pathology on cognition and the potential generational changes in cognitive reserve across sexes.
Authors
- Almudena Aguilera del Moral
- Estefania Drzewiscki
- José Enrique Arriola‐Infante (ORCID: https://orcid.org/0000-0002-3298-4601)
- F. Rodríguez Sánchez
- María del Mar Martínez‐Salmerón
- David Romera‐Morales
- Marta Rodríguez‐Camacho
- María del Mar Iglesias‐Espinosa
- Luis Andrade‐Zumárraga
- Consuelo Barranco Criado
Institutions
- Omuta hospital (JP)
- Complejo Hospitalario Torrecárdenas (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70858_106927
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00