Antimicrobial resistance and virulence patterns of Helicobacter pylori among patients with suspected peptic ulcer disease in disenfranchised settings
Our findings demonstrate the circulation of <i>H. pylori</i> among symptomatic patients with suspected peptic ulcers in Lebanon, characterized by a rich and diverse pool of virulence genes and the emergence of resistance to clarithromycin and levofloxacin. Large-scale surveillance is crucial for quantifying the burden of <i>H. pylori</i> infection, monitoring antimicrobial resistance trends, and ensuring timely updates to eradication treatment policies.
Authors
- Monzer Hamzé (ORCID: https://orcid.org/0000-0001-7466-5118)
- Kevin J. Cummings (ORCID: https://orcid.org/0000-0003-3327-596X)
- Hayssam Moubayed
- Hassan Mallat (ORCID: https://orcid.org/0000-0002-5358-4148)
- Rayane Rafei (ORCID: https://orcid.org/0000-0001-9633-1290)
- Wassim Rafei
- Joseph Awada
- Farah Majzoub
- Fouad Dabboussi (ORCID: https://orcid.org/0000-0002-9211-2370)
- Marwan Osman
Institutions
- Lebanese University (LB)
- Cornell University (US)
- Yale University (US)
- University of Tripoli Lebanon (LB)
- Montimage (France) (FR)
- Al-Salam Hospital (LB)
- Clinique de La Source (CH)
- Nini Hospital (LB)
Publication Details
- Journal
- Infectious Medicine
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1016/j.imj.2025.100232
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00