Measurement of myocardial extracellular volume fraction and cardiomyocyte diameter before and 6 months after aortic valve replacement in patients with severe aortic stenosis
Cellular hypertrophy regressed 6 months following AVR; the extracellular matrix volume did not change significantly. τ<sub>ic</sub> decreased post-AVR, indicating that the reduction in cell volume can be largely attributed to a reduction in cardiomyocyte diameter.
Authors
- Noor Sharrack (ORCID: https://orcid.org/0000-0001-5880-1722)
- David L. Buckley (ORCID: https://orcid.org/0000-0001-6659-8365)
- Sven Plein
- Peter Kellman
- Alex Makins
- John D. Biglands
Institutions
- National Institutes of Health (US)
- University of Leeds (GB)
- Leeds Teaching Hospitals NHS Trust (GB)
- National Heart, Lung, and Blood Institute (US)
Publication Details
- Journal
- Journal of Cardiovascular Magnetic Resonance
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1016/j.jocmr.2025.102679
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00