Lonely individuals show more tau pathology in Alzheimer's Disease
We found that the high loneliness level was associated with more tau pathology, especially in participants with cognitive impairment or who have Aβ pathology. These findings suggest a strong link between loneliness and tau pathology, providing novel insights into how the neuropsychiatry state affects tau aggregation in AD.
Authors
- Lizhi Guo (ORCID: https://orcid.org/0000-0002-5701-0416)
- Xin Zhou
- Tengfei Guo
- Yiying Wang
- Anqi Li
Institutions
- Chinese University of Hong Kong (HK)
- Hainan University (CN)
- Shenzhen Bay Laboratory (CN)
- Peking University Shenzhen Hospital (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_100833
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00