Sepsis‐induced systemic inflammation and tau pathology examined in the PS19 transgenic mouse model
Our findings suggest that systemic inflammation could affect lifespan and regional AT8-tau burden based on sex. Further experiments are warranted to identify cell-type specific changes to identify mechanistic links between systemic inflammation and AD-type tau pathology.
Authors
- Dina C. Nacionales
- Quan Vo (ORCID: https://orcid.org/0000-0001-5168-2628)
- Philip A. Efron (ORCID: https://orcid.org/0000-0002-3931-650X)
- L. Moldawer
- Paramita Chakrabarty (ORCID: https://orcid.org/0000-0002-6226-3776)
- Carmelina Gorski
- Kristi Biswas
Institutions
- University of Florida (US)
- Florida College (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107400
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00