Automated and Unbiased Machine Learning Predictions of Alzheimer's Risk Factors in an Ethnically Diverse Dataset using Cortical Thicknesses

In the challenging task of predicting risk factors exclusively from cortical thickness values, AutoML demonstrated its ability to adapt to each task. Despite identical input data, AutoML selected unique pipelines for 5 out of 7 tasks, highlighting the lack of a universal model and showing the potential value of AutoML in Alzheimer's research.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_100888
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Automated and Unbiased Machine Learning Predictions of Alzheimer's Risk Factors in an Ethnically Diverse Dataset using Cortical Thicknesses

Robert Leech, D H Wyllie, Philip SJ. Weston, Maitrei Kohli et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Automated and Unbiased Machine Learning Predictions of Alzheimer's Risk Factors in an Ethnically Diverse Dataset using Cortical Thicknesses

Robert Leech, D H Wyllie, Philip SJ. Weston, Maitrei Kohli, James H. Cole
article en

Abstract

In the challenging task of predicting risk factors exclusively from cortical thickness values, AutoML demonstrated its ability to adapt to each task. Despite identical input data, AutoML selected unique pipelines for 5 out of 7 tasks, highlighting the lack of a universal model and showing the potential value of AutoML in Alzheimer's research.

Alzheimer s & DementiaVol. 21(S2)
King's College London (GB), UK Dementia Research Institute (GB), The London College (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB)
Good health and well-being
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
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