Creatine to Augment Bioenergetics in Alzheimer's Disease

This pilot trial demonstrated that acute intervention with 20 g/day of CrM is feasible in patients with AD and associated with bioenergetic and cognitive improvements. These preliminary data suggest further investigation into CrM's brain target engagement and potential as an affordable adjuvant therapy is justifiable.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70858_100477
Primary Topic
Muscle metabolism and nutrition
Type
article
Field-Weighted Citation Impact
0.00
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article

Creatine to Augment Bioenergetics in Alzheimer's Disease

Matthew K Taylor
Alzheimer s & Dementia
Muscle metabolism and nutrition
article

Creatine to Augment Bioenergetics in Alzheimer's Disease

Matthew K Taylor
article en

Abstract

This pilot trial demonstrated that acute intervention with 20 g/day of CrM is feasible in patients with AD and associated with bioenergetic and cognitive improvements. These preliminary data suggest further investigation into CrM's brain target engagement and potential as an affordable adjuvant therapy is justifiable.

Alzheimer s & DementiaVol. 21(S4)
University of Kansas Medical Center (US)
Openalex Percentile: Top 34%
Muscle metabolism and nutrition
DOIOpen Access PDFOpenAlex
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Creatine to Augment Bioenergetics in Alzheimer's Disease — Matthew K Taylor · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS