Diagnosing neurodegenerative disorders using retina as an external window: A systematic review of OCT‐MRI correlations
Layer- or region-specific retinal markers are better suited for non-vascular dementias, while vascular markers more closely reflect vascular neurodegeneration. Future research must overcome several challenges including methodological heterogeneity and the complex interactions between different degenerative mechanisms. A better understanding of the associations between retinal and brain lesions could ultimately lead to the clinical use of retinal biomarkers for the early diagnosis of neurodegenerative diseases.
Authors
- Monica Lavoie (ORCID: https://orcid.org/0000-0002-7476-9782)
- Caroline Dallaire‐Théroux (ORCID: https://orcid.org/0000-0003-1729-2209)
- Ali Dirani (ORCID: https://orcid.org/0000-0003-2013-5538)
- Fei Wu
- Elodie michaud
- Frédéric Bergeron (ORCID: https://orcid.org/0000-0003-0978-7420)
- Robert Laforce (ORCID: https://orcid.org/0000-0002-2031-490X)
- Jean‐Paul Soucy
Institutions
- Montreal Neurological Institute and Hospital (CA)
- Centre hospitalier universitaire de Québec (CA)
- Kidney Foundation of Canada (CA)
- Université Laval (CA)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_098892
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00