Multicohort characterization of brain volume and cognitive decline in LATE‐NC cases with or without Alzheimer's disease pathology
In a large, multicohort study, AD and LATE-NC uniquely were associated with MTL volume and cognitive decline. Characterizing the clinical correlates of LATE-NC is essential to identifying LATE-NC during life and supporting future research into its pathogenesis.
Authors
- Michael Cuccaro
- Timothy J. Hohman (ORCID: https://orcid.org/0000-0002-3377-7014)
- Renaud La Joie (ORCID: https://orcid.org/0000-0003-2581-8100)
- Sarah Biber
- Gary W. Beecham (ORCID: https://orcid.org/0000-0002-7061-6332)
- Derek B. Archer (ORCID: https://orcid.org/0000-0001-8638-0785)
- Logan C. Dumitrescu (ORCID: https://orcid.org/0000-0002-9782-9944)
- Christos A. Davatzikos (ORCID: https://orcid.org/0000-0002-1025-8561)
- Leslie S. Gaynor (ORCID: https://orcid.org/0000-0003-1121-4365)
- Phoebe Scollard
- Alaina Durant
- Lisa Laverne Barnes
- Seo‐Eun Choi (ORCID: https://orcid.org/0000-0002-2163-688X)
- Walter W. Kukull
- Guray Erus
- Angela L. Jefferson
- Paul K Crane
- Thomas J. Montine
- Shubhabrata Mukherjee
- Julie A Schneider
- Shannon L Risacher
- David A. A. Bennett
- Mohamad Habes
- Yuhan Cui
- Michael L. Lee
Institutions
- Rush University Medical Center (US)
- University of Miami (US)
- Université de Bordeaux (FR)
- Inserm (FR)
- The University of Texas at San Antonio Health Science Center (US)
- University of California, San Francisco (US)
- University of Washington (US)
- Bordeaux Population Health (FR)
- Indiana University School of Medicine
- The University of Texas at San Antonio (US)
- Wake Forest University (US)
- Indiana University – Purdue University Indianapolis (US)
- University of Pennsylvania (US)
- Vanderbilt University Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_107276
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00