The Use of Testosterone in Women and its Impact on Quality of Life in Menopause and Beyond

In addition to estrogen and progesterone, women's ovaries secrete a whole host of other hormones, including testosterone (T), which is produced both in the ovaries and in the adrenal glands.Unfortunately, the addition of T in hormone therapy (HT) has not become a standard practice.Considering the need for individual treatment of each menopausal woman, one should also consider, in addition to classic climacteric symptoms, decreased libido and reduced sexual desire syndrome with an absence of sexual fantasies.Furthermore, emotional instability and decreased muscle strength with loss of energy are additional symptoms of T deficiency.Therefore, a global consensus was needed to definitively determine the standard, indications, and contraindications for the use of T in women during menopause.This consensus showed that, according to evidence-based medicine (EBM) standards, a confirmed indication for T use is decreased libido and reduced sexual desire syndrome with the absence of sexual fantasies in women during menopause.Moreover, it clearly showed that, with the correct concentration of T, there are no serious contraindications for T use in women.The problem remains the use of T for transdermal application, as no global pharmaceutical company has produced T in concentrations suitable for women.Therefore, we must use reduced doses of male transdermal T.